Research papers are the cornerstone of scientific communication and the “unit of currency” for the development of scientific careers. It is important that your work is understood, reproduced and adopted. Writing and reading papers are an essential part of scientific-life. It is therefore important that you read and understand them as reproduction of many science outputs are limited. We will address key elements of the clinical and basic science papers with a view to understanding reporting requirements, bias reduction and data presentation that may help inform experimental design and improve your capacity to critically appraise work. We will use examples from the Neuroimmunology that can be applied to your field of interest, journal clubs and reviewing manuscripts and grants.