Autoimmunity and/or Psychiatry
Treatment resistant psychiatric disease carries considerable morbidity and mortality. There are well described psychiatric manifestations of autoimmune disease such as cerebral lupus or autoimmune encephalitis as well as demonstrated strong associations between autoimmunity and psychiatric disease. Recently, there has been renewed interest in the possible autoimmune contribution to treatment resistant psychiatric disease and using immune modulatory therapies as an addition to standard treatment. We will review the current available modalities for investigation of neuroinflammatory disease and evidence for neuroinflammation in the psychiatric setting.